منابع مشابه
Workshop on perinatal exposure to dioxin-like compounds. I. Summary.
An international workshop reviewed 20 ongoing or recently completed studies of the effects of perinatal exposures to dioxins, dibenzofurans, and PCBs on the reproductive, endocrine, neurodevelopmental, and immune systems. Many of the observed effects are consistent with these compounds acting as "environmental hormones" or endocrine disrupters. This report summarizes the conclusions and future ...
متن کاملWorkshop on perinatal exposure to dioxin-like compounds. IV. Neurobehavioral effects.
Nine participants outlined findings in the area of neurobehavioral effects of dioxin-like compounds and presented plans for new studies. Neurobehavioral effects are among the most sensitive and well studied toxicity end points for this class of compounds. A focus of the workshop was presentation of designs for major new studies in human populations outside the United States that are intended to...
متن کاملWorkshop on perinatal exposure to dioxin-like compounds. II. Reproductive effects.
This summary report focuses on current studies on reproductive effects reported at the workshop on Perinatal Exposure to Dioxin-like Compounds and supporting data noted in the discussion. Recent laboratory studies have suggested that altered development (e.g., low birth weight, spontaneous abortion, congenital malformation) and reproductive health (e.g., fertility, sex organ development, reprod...
متن کاملWorkshop on perinatal exposure to dioxin-like compounds. V. Immunologic effects.
The immune system comprises a highly integrated network of multiple tissues and cell types with complicated interactions and effects. It is modulated by the endocrine and nervous systems and there is growing realization of its multifunctionality. The session focusing on immunologic effects of dioxin and related compounds following prenatal exposure involved a review of the immunotoxic effects t...
متن کاملWorkshop on perinatal exposure to dioxin-like compounds. VI. Role of biomarkers.
Studies of perinatal exposures to dioxin-like compounds (DLCs), coplanar polycyclic halogenated aromatics whose prototype is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), have employed a variety of outcome measures to investigate effects on the reproductive/developmental, endocrine, immune, and neurobehavioral systems. The effects include infertility, growth retardation, fetal loss, changed sexua...
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ژورنال
عنوان ژورنال: Nature
سال: 1978
ISSN: 0028-0836,1476-4687
DOI: 10.1038/276304b0